How to change the location for virtual hosts in Plesk for Windows Server?
Connect to a Plesk server via RDP.
Start Plesk Reconfigurator at Windows Start > All Programs > Plesk.
In Plesk Reconfigurator, select Change Virtual Hosts location.
Specify a new location for virtual hosts and click Next. All existing website data will be transferred to the new location as well.
Note: During this operation websites will be stopped.
Note: Network drive as virtual hosts location (e.g. NTFS hosted on AWS FSx) is not supported by Plesk yet. Vote for this feature on Plesk UserVoice.
Note: The new location folder must be empty.